Saline Creek (Mississippi River tributary)
General data
- Name: Saline Creek (Mississippi River tributary)
- Water system: Mississippi River
- Water type: River
- Progression: Mississippi River -> Gulf of Mexico -> Atlantic Ocean -> Planet Earth
- Climates: Temperate
- Continents: North America
- Countries: United States of America
Saline Creek is a creek that rises in western Ste. Genevieve County and flows east briefly passing through a portion of northern Perry County before emptying into an offshoot of the Mississippi River north of St. Mary across from Kaskaskia Island.