Owasco River
General data
- Name: Owasco River
- Water system: St. Lawrence River
- Water type: River
- Progression: Seneca River (New York) -> Oswego River (New York) -> Lake Ontario -> St. Lawrence River -> Gulf of St. Lawrence -> Atlantic Ocean -> Planet Earth
- Climates: Continental
- Continents: North America
- Countries: United States of America
Owasco River (also known as Owasco Creek, Owasco Lake Outlet, and Owasco Outlet) is a river in Cayuga County in the state of New York. The river drains Owasco Lake at Auburn and flows in a north-northwest direction before converging with the Seneca River north-northwest of Port Byron. The Owasco River Railway is named after the river.