Otay River
General data
- Name: Otay River
- Water system: Pacific Ocean
- Water type: River
- Progression: San Diego Bay -> Pacific Ocean -> Planet Earth
- Climates: Temperate
- Continents: North America
- Countries: United States of America
The Otay River is a river in southern San Diego County, California.
The 25 mi (40 km) river begins at San Miguel Mountain, flows through the Upper and Lower Otay Reservoirs, and continues on between the southern part of the Chula Vista and the Otay Mesa West district of San Diego, to its river mouth on San Diego Bay.