Mission River
General data
- Name: Mission River
- Water system: Gulf of Mexico
- Water type: River
- Source: Blanco Creek, Medio Creek
- Progression: Copano Bay -> Aransas Bay -> Gulf of Mexico -> Atlantic Ocean -> Planet Earth
- Climates: Temperate
- Continents: North America
- Countries: United States of America
The Mission River is a river located in Texas, in the United States of America. It is formed by the confluence of Blanco and Medio creeks in central Refugio County (at 28°19' N, 97°19' W) and runs southeast, past Refugio, for 24 miles (39 km) to its mouth on Mission Bay, an inlet of Copano Bay (at 28°10' N, 97°10' W). It traverses gently undulating coastal prairies surfaced by clay and loam and spotted by groves of hardwoods and pines. It is home to myriad waterfowl and native slough grasses.