Middle River (Iowa)
General data
- Name: Middle River (Iowa)
- Water system: Mississippi River
- Water type: River
- Progression: Des Moines River -> Mississippi River -> Gulf of Mexico -> Atlantic Ocean -> Planet Earth
- Climates: Temperate
- Continents: North America
- Countries: United States of America
The Middle River is a tributary of the Des Moines River in south-central Iowa in the United States. It is 123 miles (198 km) long and drains an area of 489.5 square miles (1,268 km2). Via the Des Moines River, it is part of the watershed of the Mississippi River.