Homochitto River
General data
- Name: Homochitto River
- Water system: Mississippi River
- Water type: River
- Progression: Mississippi River -> Gulf of Mexico -> Atlantic Ocean -> Planet Earth
- Climates: Temperate
- Continents: North America
- Countries: United States of America
The Homochitto River is a river in the U.S. State of Mississippi.
It flows from its source in southwest Mississippi for about 90 miles (145 km) west and south, emptying into the Mississippi River between Natchez and Woodville.