Big South Fork of the Little River
General data
- Name: Big South Fork of the Little River
- Water system: Tennessee River
- Water type: River
- Progression: Little River (Tennessee River tributary) -> Tennessee River -> Ohio River -> Mississippi River -> Gulf of Mexico -> Atlantic Ocean -> Planet Earth
- Climates: Temperate
- Continents: North America
- Countries: United States of America
The Big South Fork of the Little River in Tennessee is a major tributary of the Little River, located in the southeastern Appalachian region, mainly in Monroe County. It should not be confused with the Big South Fork of the Cumberland River in northern Tennessee/Kentucky.