Appoquinimink River
General data
- Name: Appoquinimink River
- Water system: Delaware Bay
- Water type: River
- Progression: Delaware Bay -> Atlantic Ocean -> Planet Earth
- Climates: Temperate
- Continents: North America
- Countries: United States of America
The Appoquinimink River is a river flowing to Delaware Bay in northern Delaware in the United States. The river is 15.3 miles (24.6 km) long and drains an area of 47 square miles (120 km2) on the Atlantic Coastal Plain.