Pamlico River
General data
- Name: Pamlico River
- Water system: Atlantic Ocean
- Water type: Estuary
- Progression: Pamlico Sound -> Atlantic Ocean -> Planet Earth
- Climates: Subtropical
- Continents: North America
- Countries: United States of America
The Pamlico River is a tidal river that flows into Pamlico Sound, in North Carolina in the United States. It is formed by the confluence of the Tar River and Tranters Creek.