Little Choptank River
General data
- Name: Little Choptank River
- Water system: Chesapeake Bay
- Water type: Estuary
- Progression: Chesapeake Bay -> Atlantic Ocean -> Planet Earth
- Climates: Temperate
- Continents: North America
- Countries: United States of America
The Little Choptank River is a tidal river in Dorchester County in the U.S. state of Maryland. The river rises at the confluence of Lee Creek and Gary Creek 3 miles (4.8 km) west of Cambridge.